28 articles - From Friday Oct 28 2022 to Friday Nov 04 2022
Guidelines, position statements, white papers, technical reviews, consensus statements, etc…
| Rheumatology (Oxford) |
meta-analyses and systematic reviews
RCT, clinical trials, retrospective studies, etc…
| Arthritis Care Res (Hoboken) |
Relation of temporal asymmetry during walking to 2-year knee pain outcomes in those with mild-to-moderate unilateral knee pain: an exploratory analysis from the Multicenter Osteoarthritis (MOST) Study. For those with unilateral knee pain, temporal asymmetry during walking is not associated with pain severity. However, select measures of stance and single limb support during self-selected and fast walking relate to longitudinal knee pain outcomes. |
| Arthritis Res Ther |
Assessing the causal relationships between gout and hypertension: a bidirectional Mendelian randomisation study with coarsened exposures. In this study, we showed that the liability of gout has a causal effect on hypertension, but the liability of hypertension does not have a causal effect on gout. Adequate management of gout may reduce the risk of developing hypertension. |
Differentiating tracheobronchial involvement in granulomatosis with polyangiitis and relapsing polychondritis on chest CT: a cohort study. The presence of subglottic involvement and diffuse airway involvement are the two most relevant criteria in differentiating between GPA and RP on chest CT. Although generally considered to be a highly suggestive sign of RP, posterior tracheal membrane sparing is a nonspecific and an overly subjective sign. |
PSTPIP2 regulates synovial macrophages polarization and dynamics via ERß in the joint microenvironment. Together, this study reveals that PSTPIP2 regulates synovial macrophages polarization and dynamics via ERß to form an immunological barrier (F4/80 + PSTPIP2 hi cell-enriched zone) for the joints. Thus, local modulation of PSTPIP2 expression in the joint microenvironment may be a potential strategy for controlling bone erosion in rheumatoid arthritis. PSTPIP2 regulates synovial macrophages polarization and dynamics via ERß to form F4/80 + PSTPIP2 hi cellular barrier in joint microenvironment. |
| Arthritis Rheumatol |
| Rheumatology (Oxford) |
B cell receptor profiling before and after IVIg monotherapy in newly diagnosed idiopathic inflammatory myopathies. In treatment naïve patients with newly diagnosed IIM, muscle tissue and peripheral blood share expanded BcR clones. In our study a higher cumulative frequency of dominant BcR clones in blood before treatment was associated with a higher CK and better treatment response, suggesting that response to IVIg may depend on the composition of the pre-treatment BcR repertoire. |
Changes in anti-MDA5 antibody titres and serum cytokine levels before and after diagnosis of anti-MDA5 antibody-positive dermatomyositis. The anti-MDA5 antibody titre at diagnosis may predict the clinical course. Levels of macrophage-associated cytokines significantly declined at 6 |
Comprehensive and reliable sonographic assessment and scoring system for inflammatory lesions of the pediatric ankle. A comprehensive and reliable pediatric ankle US scanning protocol and scoring system for the assessment of synovitis and tenosynovitis were successfully developed. Further validation of this scoring system may allow its use as an outcome measure for both clinical and research applications. |
COVID-19 vaccination in autoimmune diseases (COVAD) Study: vaccine safety and tolerance in rheumatoid arthritis. Despite the differences in AE frequency across different COVID-19 vaccines, al were well tolerated in patients with RA and were comparable to HCs providing reassurance to the safety of COVID-19 vaccination in them. |
Deep stratification by transcriptome molecular characters for precision treatment of patients with systemic lupus erythematosus. We developed the largest cohesive SLE transcriptomic compendium for deep stratification using the most comprehensive microarray and RNA sequencing datasets to date. This result could guide future design of molecular diagnosis and the development of stratified therapy for SLE patients. |
Diagnosing and treating ANCA-associated vasculitis: an updated review for clinical practice. ANCA and other biomarkers can be helpful in association with clinical assessment to guide diagnosis and treatment decisions. Patients should be frequently evaluated during follow-up for possible disease relapses or treatment-related morbidity, and for monitoring damage accrual, especially metabolic and cardiovascular damage. |
Plenty of the editorials are available as full text through the publisher website using the provided link
misc publications eg case reports, tools of the trade, images of the month, etc…
| Rheumatology (Oxford) |
Letters to the editors and authors’ replies
| Arthritis Care Res (Hoboken) |
| Arthritis Res Ther |
Comment on "The effect of disease-modifying anti-rheumatic drugs on skeletal muscle mass in rheumatoid arthritis patients: a systematic review with meta-analysis". In this regard, it may not be appropriate to simultaneously perform a meta-analysis of skeletal muscle mass determined by DEXA and BIA. With the issues described above, we conclude by recommending additional investigations to strengthen the arguments presented by this valuable meta-analysis. |